Mechanical Modulation of Receptor-Ligand Interactions at Cell-Cell Interfaces
نویسندگان
چکیده
منابع مشابه
Mechanical modulation of receptor-ligand interactions at cell-cell interfaces.
Cell surface receptors have been extensively studied because they initiate and regulate signal transduction cascades leading to a variety of functional cellular outcomes. An important class of immune receptors (e.g., T-cell antigen receptors) whose ligands are anchored to the surfaces of other cells remain poorly understood. The mechanism by which ligand binding initiates receptor phosphorylati...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.02.006